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カタログ番号 | 製品名 | 別名 | ターゲット |
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T7714 | Temocapil | Tyrosinase | |
Temocapril is an inhibitor of tyrosine kinase. | |||
T6698 | Temocapril hydrochloride | CS-622 HCl,Acecol,Temocapril HCl,CS-622 | RAAS |
Temocapril hydrochloride (CS-622 HCl), the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension. | |||
T17028 | Tefinostat | CHR-2845 | HDAC |
Tefinostat (CHR-2845) is a potent monocyte/macrophage-targeted histone deacetylase (HDAC) inhibitor. Tefinostat is cleaved to the active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1).Tefino... | |||
T15082 | DDAO | Others | |
DDAO is a promising near-infrared (NIR) red fluorescent probe with long emission wavelength (λem = 656 nm) and tunable excitation wavelength (600-650 nm). It can de desiged for detection of the activities of different en... | |||
T63015 | Pancreatic lipase/Carboxylesterase 1-IN-1 | ||
Pancreatic lipase/Carboxylesterase 1-IN-1 (Compound 39) is a potent, dual inhibitor of pancreatic lipase (PL) and human carboxylesterase 1A (hCES1A), acting on PL (IC50: 2.13 μM) and hCES1A (IC50: 0.055 μM). | |||
T81924 | LK-44 | ||
Compound 44 (hCES2A-IN-2) is an orally active inhibitor of human carboxylesterase 2 (hCES2A) with an IC50 of 5.02 μM, which ameliorates Irinotecan-induced delayed diarrhea [1]. | |||
T82231 | HCES2-IN-1 | ||
hCES2-IN-1 (Compound 24) is a reversible, selective inhibitor of the human carboxylesterase 2 (hCES2) enzyme, exhibiting an IC50 of 6.72 μM. This compound diminishes hCES2 levels in vivo and demonstrates efficacy in alle... | |||
T74629 | Benz-AP | ||
Benz-AP, a potent photosensitizer, generates singlet oxygen inversely related to Human carboxylesterase 2 (hCES2) activity, showcasing enhanced photocytotoxicity in cancer cells within low hCES2 environments. Moreover, u... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T75541 | Tanshinone IIA anhydride | ||
Tanshinone IIA anhydride is a potent, irreversible inhibitor of human carboxylesterase (CE), exhibiting inhibitory constants (K i values) of 1.9 nM for human CE1 and 1.4 nM for human intestinal CE (hiCE), respectively [1... | |||
TN1783 | Isolicoflavonol | Lipid | |
Isolicoflavonol is a potential cancer chemopreventive agent. |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-01776 | Carboxylesterase 2/CES2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Carboxylesterase 2/CES2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.4 kDa and the accession number is O00748-1. | |||
TMPH-01825 | NOTUM Protein, Human, Recombinant (His) | Human | E. coli |
Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient bindin... | |||
TMPK-01523 | Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi) | Human & Mouse | HEK293 Cells |
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en... | |||
TMPK-01522 | Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi) | Human & Mouse | HEK293 Cells |
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en... | |||
TMPK-01535 | Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi) | Human & Mouse | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... | |||
TMPK-01534 | Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi) | Human & Mouse | HEK293 Cells |
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel... |